Van Dongen HP, et al. The cumulative cost of additional wakefulness. Sleep. 2003;26:117-26.(健康成人48人。6時間以下の睡眠を14日続けると、認知成績が日ごとに低下し、本人の眠気の自覚はほとんど増えなかった。対象は21〜38歳)
Lim J, Dinges DF. A meta-analysis of the impact of short-term sleep deprivation on cognitive variables. Psychol Bull. 2010;136:375-89.(影響がとくに大きいのは単純な注意)
Baglioni C, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011;135:10-9.(不眠→うつ病 オッズ比 2.60)/ Li L, et al. Insomnia and the risk of depression: a meta-analysis of prospective cohort studies. BMC Psychiatry. 2016;16:375.(相対リスク 2.27)
Irwin MR, et al. Prevention of incident and recurrent major depression in older adults with insomnia: a randomized clinical trial. JAMA Psychiatry. 2022;79:33-41.(60歳以上291人。3年までのうつ病発症 12.2% vs 25.9%。追跡の脱落が多い)
Sabia S, et al. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun. 2021;12:2289.(英国7,959人・約25年)/ Ohara T, et al. Association between daily sleep duration and risk of dementia and mortality in a Japanese community. J Am Geriatr Soc. 2018;66:1911-8.(久山町研究。5時間未満で認知症 ハザード比 2.64)いずれも観察研究。
McLaren DM, et al. Behavioural components of cognitive behavioural therapy for insomnia in older adults. J Sleep Res. 2023;32:e13843.(刺激制御法・睡眠制限法)
Qaseem A, et al. Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2016;165:125-33.(すべての成人の慢性不眠に、最初の治療として CBT-I を強く推奨)